Endometriosis is a disease affecting an estimated 5.5 million women in the United States. It is a leading cause of infertility, chronic pelvic pain and hysterectomy.
With Endometriosis, tissue, like the endometrium (the tissue inside the uterus which builds up and is shed each month during menses), is found outside the uterus in other areas of the body. These foreign tissues respond to hormonal commands each month and break down and bleed. However, unlike the endometrium, these tissue deposits have no way of leaving the body. The result is internal bleeding, degeneration of blood and tissue shed from the growths, inflammation of the surrounding areas, expression of irritating enzymes and formation of scar tissue. In addition, depending on the location of the growths, interference with the bowel, bladder, intestines and other areas of the pelvic cavity can occur. Endometriosis has even been found lodged in the skin and at other outer pelvic locations like the arm, leg and even the brain.
Most physicians agree estrogen is responsible for the proliferation of endometriosis. During pregnancy, endometriosis will often disappear, only to return again after pregnancy. This suggests hormonal involvement and that the high progesterone levels produced in pregnancy play an important part in controlling the disease. With this in mind, medical treatments attempt to create a state of pseudo pregnancy, with long periods of supplemented progestins, such as birth control pills, to simulate the high progesterone levels of pregnancy. Unfortunately, these synthetic hormonal medications are often accompanied by side effects ill-tolerated by many women. Such drugs have included Lupron™, Zoladex™ and Depo-Provera™. While these drugs do inhibit estrogen function, they also occupy binding sites for progesterone, thereby depressing a woman’s natural progesterone function as well. Other than continual pregnancy and total hysterectomy, traditional medical treatments for endometriosis are temporary.
Lately, physicians have recognized the significance of hormonal balance relating to endometriosis and the resulting therapy involves the use of saliva hormone testing. Levels of estrogen and progesterone can easily be tested by saliva assay. With the low rate of success offered by traditional medicine, more women are turning to Bio-identical Hormone Replacement Therapy to regain their health.
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